您现在的位置是:Chip assesses cancer treatment efficacy with blood draw >>正文
Chip assesses cancer treatment efficacy with blood draw
上海品茶网 - 夜上海最新论坛社区 - 上海千花论坛51人已围观
简介By subscribing, you agree to our Terms of Use and Policies You may unsubscribe at any time.By employ...
By subscribing, you agree to our Terms of Use and Policies You may unsubscribe at any time.
By employing a microchip called 'GO chip' for the analysis of blood samples, physicians could assess the concentration of cancer cells in a patient's bloodstream, offering insights into treatment efficacy as early as the fourth week.
The 'GO chip' was created in a laboratory by the University of Michigan researchers. The chip is like a special tool that catches cancer cells from the blood.
It works a bit like flypaper catching flies, but this chip only grabs the specific cancer cells we're looking for. The chip has tiny sheets made of graphene oxide with antibodies on them.
These antibodies recognize special markers on the surface of cancer cells. When blood flows through the chip, the antibodies trap the cells, making a concentration that can be studied.
See Also Related- 3D-printed body-on-chip may replace animal models in drug testing
- Tiny surgical robot could travel deep into lungs to detect and treat cancer one day
- Cancer treatment over 2x more effective with engineered mitochondria
This helps the researchers count the cells, confirm they are cancerous, and determine how their chemistry is different in different patients and stages of treatment.
"Currently, there's typically a wait of weeks to months before we can fully assess the effectiveness of cancer treatment," said Shruti Jolly, professor of radiation oncology, associate chair of community practices at U-M and co-corresponding author of the study.
"However, with this chip, we may be able to sidestep prolonged, ineffective therapy and quickly pivot to alternatives, thus saving patients from needless side effects," she added.
The study proposes that this information empowers healthcare professionals to tailor cancer treatments based on individual patient requirements, thereby enhancing overall treatment outcomes.
The study zeroed in on lung cancer
The study looks at very specific lung cancer patients (30 percent of all lung cancer patients) who have locally advanced non-small cell lung cancer that cannot be surgically removed.
The usual treatment involves a mix of chemotherapy and radiation, followed by a year of other treatments. To make treatments more personalized, it's important to predict if the cancer will spread early on during the initial treatment.
The conventional monitoring methods involve imaging scans and needle biopsies, which are costly, time-consuming, invasive, and minimally repeatable. The proposed solution in the study is a liquid biopsy via blood samples.
Circulating tumor cells (CTCs) are cells that come from tumors and can be found in a simple blood draw. Catching these cells is tricky because there aren't many of them present. Still, the GO chip uses immunoaffinity to capture CTCs on the surface of the device with high purity and sensitivity.
In their study, the researchers used the GO chip to find CTCs in patients with stage III lung cancer who hadn't started treatment yet.
They observed that if the count of cancer cells in a patient's bloodstream doesn't drop by at least 75 percent by the fourth week of treatment, there's a higher likelihood that the cancer may persist even after the completion of the treatment.
This finding carries significant implications for understanding and predicting treatment outcomes in cancer patients.
The study was published in Cell Reports.
Tags:
转载:欢迎各位朋友分享到网络,但转载请说明文章出处“上海品茶网 - 夜上海最新论坛社区 - 上海千花论坛”。http://www.jz08.com.cn/news/44538.html
相关文章
Cosmos gains a tenth today: here’s where to buy Cosmos now
Chip assesses cancer treatment efficacy with blood drawThe live Cosmos price today is just under $25 with a 24-hour trading volume of $794.36 million. The...
阅读更多
A Fundamental Analysis of Tron (TRX)
Chip assesses cancer treatment efficacy with blood drawTron (TRX) is faced directly with eliminating middlemen for content creators and entertainers.TRX cl...
阅读更多
Bitcoin crosses $13k as PayPal enters the crypto market
Chip assesses cancer treatment efficacy with blood drawNews of PayPal entering the cryptocurrency market triggered a rally in the markets, with Bitcoin sur...
阅读更多
热门文章
- Brazil Sets Release Of Digital Real By 2022
- Shiba Inu price: Can this Shibarium milestone ignite SHIB?
- South Korea To Launch Blockchain Voting System For Elections
- Elon Musk's X platform has payments licenses in seven US states
- The synthetic bitcoin market rises by 83% to hold over $700 million on the Ethereum blockchain
- Experts Predict Bitcoin Will Hit $100, 000 – But When Exactly?
最新文章
Singapore High Court rules crypto not different from fiat money or shells
Tether’s excess reserves increased by $850M to $3.3B in Q2
13 banks to participate in Russia's CBDC pilot program
Heavy sell
aelf (ELF) price surges amid upcoming Metaverse Hackathon Top of OASIS
CHANCER price prediction: Chancer’s presale surpasses $1.1 million